Causes of Infertility in Men
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Most common causes of infertility in men are explained in this article. An
exact cause is not known in some cases (known as unexplained infertility).
There are four types of sperm disorders: low sperm count known as
Oligospermia, complete absence of sperm cells referred to as Azoospermia, poor sperm motility known as
Asthenospermia (inability of the sperm to move fast enough or to move in a straight line) and abnormal sperm
morphology referred to as Teratospermia (abnormally shaped sperm). All these conditions interfere with a sperm's
ability to reach and fertilize an egg and are regarded as major causes of infertility in men.
Sperm disorders are results of: birth defects, hormone deficiency in the pituitary
gland or hypothalamus, aging, exposure to harmful substances, radiations or high temperature, chemotherapy,
sexually transmitted diseases and other lifestyle factors such as smoking, alcohol abuse, use of marijuana or
cocaine, excessive exercise, bike riding, stress etc.
Most common structural disorders that can cause infertility in men are:
Blocks in Vas Deferens
or Ejaculatory Duct: Sperm are transported from testes to penis through vas deferens (a pair of tubes, one
from each testicle) and ejaculatory duct. A genetic defect
such as cystic fibrosis (click for more information), scarring from tuberculosis or sexually transmitted
diseases can cause blockages in vas deferens or ejaculatory duct.
This can result in low sperm count or complete absence of sperm cells
Varicocele: is enlargement
of varicose veins around testes. This raises temperature in testes, thereby causing reduced sperm count and
abnormal sperm morphology.
Torsion: is characterized by a
tissue abnormality which allows testes to twist inside the scrotum, damaging
blood vessels and causing swelling. This can lead to sperm
Cryptorchidism: refers to a condition usually
seen in new born babies when one or both testicles fail to descend from abdomen into the scrotum.
Cryptorchidism can cause low sperm count and/or poor sperm quality. There are
medical treatments available for cryptorchidism.
Hypospadias: is a birth defect in which
the urethral opening is not at the tip of the penis. This condition
can interfere with transportation of sperm from testes to penis.
Hypospadias can be surgically corrected.
Genetic disorders such as the ones listed below can lead to
Klinefelter Syndrome: Men with Klinefelter Syndrome have two X chromosomes and one Y chromosome (instead of one X and one Y).
This can lead to destruction of testicular structures, causing infertility. Klinefelter syndrome can
be diagnosed by chromosome analysis and treatments are available if detected in early stages. Click
symptoms of Klinefelter syndrome for more information.
Polycystic Kidney Disease:
is characterized by growth of cysts in kidneys and other organs. If these cysts start
to develop in the reproductive tract, it can lead to infertility.
Syndrome: is a rare disorder that can harmfully affect sperm
motility (ability of the sperm to move fast enough or to move in a straight line).
Erectile dysfunction, also known as impotence is the inability to develop or maintain an
erection of the penis. This condition prevents successful ejaculation in men, leading to infertility. Causes
of erectile dysfunction include: anxiety, stress, guilt, diabetes, alcohol abuse, obesity, high blood pressure,
heart and vascular disease, hormonal problems, injuries to pelvic area or
spinal cord and some prescription drugs such as diuretics, antihypertensives, antipsychotics, antidepressants
A condition in which ejaculation happens before a man fully inserts his penis to partner's vagina. This can cause infertility, since sperm are not able
to move through vagina towards fallopian tube to reach the egg and fertilize
In this condition, muscles of the bladder
dysfunction and sperm are forced to flow backward into the urinary bladder instead of moving forward to the penis. This could result in low ejaculate volume,
low sperm count, low sperm quality and cloudy urine
after ejaculation. Retrograde
ejaculation can be caused by surgeries to bladder,
prostate, urethra or spinal cord,
diabetes, aging, use of blood pressure medications, tranquilizers and
certain antipsychotic drugs.
Human body may develop antibodies that mistakenly target and fight sperm
cells treating them as foreign bodies. This happens most commonly after a vasectomy (click for more information), injury to testes or infection.
Other causes of infertility in men
Other causes include: tight underwear, malnutrition and anaemia, obesity, injuries
to testes, anabolic steroid use, hot baths, imbalances in hormones produced by the pituitary gland or thyroid
gland, infections in the reproductive tract, aging, exposure to harmful substances, exposure to radiations or high
temperature, chemotherapy, sexually transmitted diseases, lifestyle factors such as smoking, alcohol abuse, use of
marijuana or cocaine, excessive exercise, bike riding, stress and diseases such as mumps, tuberculosis, gonorrhea
Please click symptoms
of infertility in men, infertility
test for men, infertility treatment for men for more information on these topics
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